In microdialysis,
A) an animal is placed in a stereotaxic apparatus while measurements are taken.
B) large quantities of fluid must be collected for HPLC analysis.
C) analysis of the contents of the extracellular fluid can be made.
D) chromatography separates substances only by ionic charge, and not by size.

Question

Quizplus · Accepted Answer

Microdialysis is a technique used to sample the extracellular fluid in vivo. By inserting a small probe (dialysis membrane) into the extracellular space, substances from this area can passively diffuse into the probe and be collected for analysis. Therefore, analysis of the contents of the extracellular fluid can be made using microdialysis. Choices A, B, and D are not correct because they do not accurately describe the process of microdialysis.

In Microdialysis