In a patient with spinocerebellar ataxis, which is characterized by poor fine motor control and coordination, which GABA pathway is affected?
A) Purkinje cells projecting to deep cerebellar nuclei and the brainstem
B) Neural pathway from the entopeduncular nucleus to the lateral habenula
C) GABAgeric neurons projecting to the globus pallidus
D) GABAgeric neurons projecting to the sustantia nigra

Question

Quizplus · Accepted Answer

Spinocerebellar ataxia is characterized by poor fine motor control and coordination. The Purkinje cells projecting to deep cerebellar nuclei and the brainstem are responsible for fine motor control and coordination. In spinocerebellar ataxia, the Purkinje cells are damaged, resulting in poor motor control and coordination. Thus, option A is the correct choice. Option B pertains to pathways related to reward and addiction, while option C and D pertain to pathways involved in the basal ganglia, which are not typically involved in spinocerebellar ataxia.

In a Patient with Spinocerebellar Ataxis, Which Is Characterized by Poor