Tolerance to opiate effects
A) is primarily due to increased rate of metabolism.
B) develops quite gradually over time.
C) is not specific to a given receptor type.
D) occurs rapidly for analgesic effects and slowly for constipating effects.

Question

Quizplus · Accepted Answer

Tolerance to opiates develops at different rates for different effects; analgesic tolerance develops quickly, while tolerance to constipating effects develops more slowly.

Tolerance to Opiate Effects