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EcoRI Restriction Mapping on a Sample of a Large Piece

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EcoRI restriction mapping on a sample of a large piece of DNA resulted in six distinct bands following agarose gel electrophoresis. Similar mapping on an identical sample that was subjected to high intensity ultraviolet light resulted in only four distinct bands. What might best explain the reduction in the number of detectable bands in the UV light-treated sample?

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EcoRI specifically cleaves DNA at GAATTC...

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