In RNA interference experiments, siRNAs homologous to known mRNAs inhibit expression of the proteins by what mechanism?
A) They form double-stranded RNA molecules that get degraded in the cytoplasm.
B) They form double-stranded RNA molecules that block the complete mRNA form traversing through the ribosomal complex.
C) They form double-stranded RNA molecules in pre-spliced primary RNA and prevent passage from the nucleus to the cytoplasm.
D) They form double-stranded RNA molecules in pre-spliced primary RNA and prevent the splicing out of introns.

Question

Quizplus · Accepted Answer

siRNAs function by forming double-stranded RNA molecules that are recognized and degraded by the cellular machinery in the cytoplasm, thus preventing the mRNA from being translated into protein.

In RNA Interference Experiments, SiRNAs Homologous to Known MRNAs Inhibit