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In Vitro Experiments Have Shown That Formation of the Preinitiation

Question 95

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In vitro experiments have shown that formation of the preinitiation transcription complex on RNA polymerase II promoters requires the dephosphorylated form of the RNA polymerase II large subunit, whereas the phosphorylated form is associated with elongating complexes. Describe how the timing of phosphorylation might influence gene transcription.

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If phosphorylation occurred before the f...

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