The directionality of nuclear transport is determined by _______ in the nucleus and _______ in the cytosol.
A) high Ran; low Ran
B) low Ran; high Ran
C) high Ran/GTP; high Ran/GDP
D) high Ran/GDP; high Ran/GTP

Question

Quizplus · Accepted Answer

The directionality of nuclear transport is determined by the concentration of Ran/GTP in the nucleus and Ran/GDP in the cytosol. Ran/GTP is high in the nucleus, which facilitates the release of import cargo and the binding of export cargo, while Ran/GDP is high in the cytosol, which facilitates the release of export cargo and the binding of import cargo.

The Directionality of Nuclear Transport Is Determined by _______ in the Nucleus