Proteins are translocated into the ER lumen
A) by flippases.
B) through an aqueous channel created by the Sec61 protein.
C) by being pushed by translation through the lipid bilayer of the ER membrane.
D) by being pulled by BiP across the lipid bilayer of the ER membrane.

Question

Quizplus · Accepted Answer

Proteins are translocated into the ER lumen through an aqueous channel created by the Sec61 protein. This channel allows the protein to pass through the hydrophobic region of the lipid bilayer and into the ER lumen. Flippases and BiP are not involved in the translocation process, and proteins are not pushed through the lipid bilayer by translation.

Proteins Are Translocated into the ER Lumen