Polypeptides inside the ER are usually smaller than polypeptides synthesized from the same mRNA that have not entered the ER.

Question

Quizplus · Accepted Answer

Polypeptides inside the ER undergo folding, processing, and modification, which can lead to their size being reduced compared to their initial length. Additionally, the presence of signal peptides and ER retention signals can cause premature termination of translation, resulting in smaller polypeptides.

Polypeptides Inside the ER Are Usually Smaller Than Polypeptides Synthesized