By which mechanism do selective serotonin reuptake inhibitors (SSRI) improve depression?

Question

Quizplus · Accepted Answer

Depression is thought to be related to lowered availability of the neurotransmitter serotonin. SSRIs act by blocking reuptake of serotonin, leaving a higher concentration available at the synaptic cleft. SSRIs prevent destruction of serotonin. SSRIs have little or no effect on acetylcholine and dopamine production. SSRIs do not produce muscarinic or ?1 norepinephrine blockade.

By Which Mechanism Do Selective Serotonin Reuptake Inhibitors (SSRI) Improve