Trinucleotide CTG repeat expansion plays a role in the pathogenesis of which of the following muscle diseases?
A) Duchenne muscular dystrophy
B) Becker muscular dystrophy
C) Autosomal dominant limb girdle muscular dystrophy
D) Autosomal recessive limb girdle muscular dystrophy
E) Myotonic dystrophy

Question

Quizplus · Accepted Answer

The trinucleotide CTG repeat expansion on chromosome 19q13.2-13.3 affecting the dystrophia myotonia-protein kinase gene is the genetic basis of myotonic dystrophy.

Trinucleotide CTG Repeat Expansion Plays a Role in the Pathogenesis