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Association Studies Compare Affected Individuals from Different Families with Unaffected

Question 42

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Association studies compare affected individuals from different families with unaffected individuals, seeking to find genetic differences between those with and without a behavior disorder. Given the size and complexity of the human genome, do you think this approach can be used to systematically scan the genome for loci controlling behavior? How will you know when you have found one? How do you differentiate between polymorphisms and genuine differences?

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Association studies can be a useful appr...

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