The primary reason for evaluating alpha-fetoprotein (AFP) levels in maternal serum is to determine whether the fetus has which condition?
A) Hemophilia
B) Sickle cell anemia
C) A neural tube defect
D) Abnormal lecithin-to-sphingomyelin ratio

Question

Quizplus · Accepted Answer

An open neural tube allows a high level of AFP to seep into the amniotic fluid and enter the maternal serum. Hemophilia is a genetic defect and is best detected with chromosomal studies, such as chorionic villus sampling or amniocentesis. Sickle cell anemia is a genetic defect and is best detected with chromosomal studies such as chorionic villus sampling or amniocentesis. L/S ratios are determined with an amniocentesis and are usually performed in the third trimester.

The Primary Reason for Evaluating Alpha-Fetoprotein (AFP) Levels in Maternal