Which analysis of maternal serum is the best predictor of chromosomal abnormalities in the fetus?
A) Biophysical profile
B) Multiple-marker screening
C) Lecithin-to-sphingomyelin ratio
D) Blood type and crossmatch of maternal and fetal serum

Question

Quizplus · Accepted Answer

Maternal serum can be analyzed for abnormal levels of alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), inhibin A, and estriol. The multiple-marker screening may predict chromosomal defects in the fetus. The biophysical profile is used to evaluate fetal status during the antepartum period. Five variables are used; however, none are concerned with chromosomal problems. The lecithin-to-sphingomyelin ratio is used to determine fetal lung maturity. The blood type and crossmatch will not predict chromosomal defects in the fetus.

Which Analysis of Maternal Serum Is the Best Predictor of Chromosomal