Destruction of muscle fibers in polymyositis is characterized by a release of enzymes,the most specific for muscle disease of which is:
A) Lactate dehydrogenase
B) Acid phosphatase
C) Alkaline phosphatase
D) Creatine kinase
E) Alanine aminotransferase

Question

Quizplus · Accepted Answer

Creatine kinase (CK) is an enzyme found in high concentrations in skeletal muscles. The destruction of muscle fibers in polymyositis results in the release of CK into the bloodstream, making it the most specific enzyme for muscle disease. Elevated levels of CK can be used as a diagnostic marker for polymyositis. Lactate dehydrogenase (LDH) and acid phosphatase can also be elevated in polymyositis, but they are less specific for muscle disease. Alkaline phosphatase and Alanine aminotransferase (ALT) are enzymes that are not specific to muscle and are typically used to assess liver function.

Destruction of Muscle Fibers in Polymyositis Is Characterized by a Release