Destruction of muscle fibers in polymyositis is characterized by a release of enzymes,of which the most specific for muscle disease is:
A) Lactate dehydrogenase
B) Acid phosphatase
C) Alkaline phosphatase
D) Creatine kinase
E) Alanine aminotransferase

Question

Quizplus · Accepted Answer

Creatine kinase is the most specific enzyme released during muscle fiber destruction in polymyositis. Elevations in lactate dehydrogenase, acid phosphatase, and alanine aminotransferase can also occur in muscle disease, but are less specific than creatine kinase. Alkaline phosphatase is not typically elevated in muscle disease, and is more commonly associated with liver and bone disorders.

Destruction of Muscle Fibers in Polymyositis Is Characterized by a Release