Endorphins create neural activity at the pain gate with which nociceptive messages must compete for the gate's limited "entry space" to the brain.

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Endorphins, which are natural painkillers produced by the body, work by creating neural activity at the pain gate, a mechanism in the spinal cord that controls the flow of pain signals to the brain. They compete with nociceptive (pain) messages for access to this gate, effectively reducing the perception of pain.

Endorphins Create Neural Activity at the Pain Gate with Which