Cystic fibrosis is caused by a recessive loss-of-function mutation that encodes a protein called the ________.
A) cystic fibrosis transmembrane ion channel
B) chloride ion transmembrane conductance regulator
C) cystic fibrosis transmembrane conductance regulator
D) cystic fibrosis ion channel regulator

Question

Quizplus · Accepted Answer

Cystic fibrosis is caused by a mutation in the CFTR (cystic fibrosis transmembrane conductance regulator) gene, which encodes the CFTR protein. This protein is responsible for regulating the movement of chloride ions in and out of cells, and mutations in CFTR lead to the buildup of thick mucus in the lungs, pancreas, and other organs, resulting in the classic symptoms of cystic fibrosis. Choices A, B, and D are incorrect because they do not accurately name the protein that is affected by the CFTR gene mutation.

Cystic Fibrosis Is Caused by a Recessive Loss-Of-Function Mutation That