A genetic male mouse given an antagonist to AMH during fetal life will most likely possess _______ internal reproductive structures and _______ external genitalia.

Question

Quizplus · Accepted Answer

AMH (Anti-Müllerian Hormone) is responsible for the regression of the Müllerian ducts during male fetal development. Blocking AMH action would allow the Müllerian ducts to persist, leading to the development of both male (from the Wolffian ducts, which develop independently of AMH) and female (from the unregressed Müllerian ducts) internal reproductive structures. However, external genitalia development is influenced by androgens, not AMH, so the external genitalia would still develop as male.

A Genetic Male Mouse Given an Antagonist to AMH During