What are the models for small-molecular-weight absorption, high-molecular-weight absorption and protein absorption by the ocular route?

Question

Quizplus · Accepted Answer

The Answer is The highly hydrated eye absorbs acetaminophen as a low molecular weight compound, 120 kDa dextran as a high molecular weight chemical, and insulin as its model protein. There are important species differences in the thickness of the sclera (larger in pig and similar in rabbit) that alter the absorption profile. However, the rabbit eye is not a good model for absorption of a gellan gum formation of technetium-99m labeled diethylenetriaminepentaacetic acid compared to the same compound in isotonic saline, as the human retains the gum formation better.

What Are the Models for Small-Molecular-Weight Absorption, High-Molecular-Weight Absorption and Protein