In Hodgkin lymphoma, B cells can become defective as a result of:
A) T-cell inactivation of B cells.
B) premature apoptosis due to lack of differentiation.
C) errors in immunoglobulin gene arrangements.
D) enhanced conversion into plasma B memory cells.

Question

Quizplus · Accepted Answer

In Hodgkin lymphoma, B cells often become defective due to errors in immunoglobulin gene arrangements, which can lead to the development of malignant Reed-Sternberg cells.

In Hodgkin Lymphoma, B Cells Can Become Defective as a Result