The master gland that acts in response to stimuli from the hypothalamus is the:

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The pituitary gland is often referred to as the "master gland" as it secretes hormones that regulate many other endocrine glands throughout the body. It is controlled by the hypothalamus, which sends signals to the pituitary gland to release or inhibit the release of certain hormones, depending on the body's needs. The thyroid gland is responsible for regulating metabolism and is controlled by the pituitary gland, which releases thyroid-stimulating hormone (TSH). The pineal gland produces melatonin and is not directly controlled by the hypothalamus. The parathyroid glands regulate calcium levels in the blood and are also not directly controlled by the hypothalamus.

The Master Gland That Acts in Response to Stimuli from the Hypothalamus