When you are logged on to the vCenter Server system using the Web Client, vCenter Server passes commands to the ESXi host through the vpxa process.

Name: When you are logged on to the vCenter Server system using the Web Client, vCenter Server passes commands to the ESXi host through the vpxa process.
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The vCenter Server communicates with ESXi hosts through the vpxa process (VMware vCenter Server Agent), which acts as an intermediary to relay commands from the vCenter Server to the ESXi host.

When You Are Logged on to the VCenter Server System