In sickle cell anemia, a ____ mutation in the β-globin gene eliminates a ____.
A) single base-pair; restriction site
B) frameshift; restriction site
C) nonsense; promoter region
D) single base-pair; promoter region
E) nonsense; restriction site

Question

Quizplus · Accepted Answer

A single base-pair mutation in the β-globin gene causes sickle cell anemia by eliminating a restriction site, which is used as a molecular marker for the disease. This mutation does not affect the promoter region, cause a frameshift, or introduce a nonsense mutation.

In Sickle Cell Anemia, a ____ Mutation in the β-Globin