Topoisomerase functions by ____.
A) creating cuts in the DNA to relieve over-twisting and strain ahead of the replication fork
B) binding DNA polymerase to hold it tightly to the template DNA
C) unwinding the DNA double helix to expose the template strands for replication
D) binding the newly synthesized DNA to re-twist it into a double helix after replication
E) reading the DNA template and synthesizing a complementary strand of DNA

Question

Quizplus · Accepted Answer

Topoisomerase works by making cuts in the DNA strand to relieve the stress caused by over-twisting or supercoiling, which occurs ahead of the replication fork during DNA replication. This process helps in preventing the DNA from becoming too tangled or broken during replication.

Topoisomerase Functions by ____