One model to explain the inhibition of enzymes involves having the inhibitor bind to the enzyme at a site distant from the active site.The enzyme then changes shape so that the substrate no longer fits into the active site.

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Quizplus · Accepted Answer

This is correct. This model is known as the allosteric model of enzyme inhibition, where the inhibitor binds to a regulatory site on the enzyme, causing a conformational change that affects the active site and prevents substrate binding.

One Model to Explain the Inhibition of Enzymes Involves Having