In a case‐control study of the association between residence near a hazardous waste site and leukaemia, selection bias is likely to be a problem because:
A)People with leukaemia may be more likely to participate than controls recruited from the general population
B)People with leukaemia living near a hazardous waste site may be more likely to participate than people living further away.
C)People without leukaemia living near a hazardous waste site may be more likely to participate than people living further away
D)All of the above

Question

Quizplus · Accepted Answer

All of the above.In case‐control studies, cases are often more likely to
participate than controls, perhaps for reasons of wanting to understand (or contribute
to an understanding of) the disease.Similarly, in this study, both cases and controls may
be more likely to have an interest in participating in a study about something that
relates directly to their neighbourhood, than those who live in other neighbourhoods.
These factors associated with participation appear to be associated with both the
exposure and the outcome, and so may lead to spurious associations.

In a Case‐control Study of the Association Between Residence near a Hazardous