If a certain isoform of myosin II is depleted from a cell, stress fibers are lost and focal adhesions disappear. If these cells are placed on a surface coated with an array of flexible pillars to measure traction forces, would you expect the traction to increase (I) or decrease (D) in these cells compared to wild-type cells? Write down I or D as your answer.

Question

Quizplus · Accepted Answer

With the loss of the stress fibers and focal adhesions as a result of the depletion of the myosin isoform, the traction forces on the substratum are expected to decrease compared to normal cells.

If a Certain Isoform of Myosin II Is Depleted from a Cell