In the presence of ATP in a flagellum, an axonemal dynein that is interacting through its tail with the A microtubule of a peripheral doublet can push this doublet toward the ...(1) of the flagellum, but due to the presence of linking proteins such as ...(2), this force is converted into a bending motion.
A) (1) tip; (2) nexin
B) (1) base; (2) nexin
C) (1) tip; (2) nebulin
D) (1) base; (2) nebulin
E) (1) tip; (2) tau

Question

Quizplus · Accepted Answer

The dynein tail domain is bound to the A microtubule of one doublet, while the motor domain interacts with the B microtubule of the neighboring doublet. The former doublet is pushed toward its minus end (and the base of the flagellum) by the minus-end directed movement of the motor domain on the latter doublet. Proteins like nexin prevent such sliding, directing the force into a bending motion.

In the Presence of ATP in a Flagellum, an Axonemal