What would most likely trigger the peripheral chemoreceptors when uncontrolled diabetes is present?
A) excessive H+ accumulation
B) low PaCO₂
C) low H+ levels in the blood
D) high PaCO₂

Question

Quizplus · Accepted Answer

In uncontrolled diabetes, due to the lack of insulin or insulin resistance, the body cannot effectively utilize glucose for energy. As a result, there is an increase in the breakdown of fats to provide energy, leading to the accumulation of acidic ketone bodies (acetoacetate, beta-hydroxybutyrate) in the blood. This accumulation of acids lowers the blood pH, leading to excessive H+ accumulation. The peripheral chemoreceptors in the carotid and aortic bodies are sensitive to changes in arterial blood pH and would be triggered by the excessive H+ accumulation in uncontrolled diabetes.

What Would Most Likely Trigger the Peripheral Chemoreceptors When Uncontrolled