The perforin-granzyme pathway involves
A) the production of fever, which kills the pathogen.
B) the production of antibodies toward the invading pathogen.
C) the synthesis of special cell-killing proteins that act on infected or abnormal cells.
D) presenting the foreign antigen to B cells.
E) binding CD95L to infected cells, which eventually leads to cell apoptosis.

Question

Quizplus · Accepted Answer

The perforin-granzyme pathway involves the synthesis of special cell-killing proteins (like perforin and granzyme) that act on infected or abnormal cells. These proteins form pores in the cell membrane of the target cell, allowing granzyme to enter the cell and trigger cell death (apoptosis). This pathway is a key defense mechanism used by T cells and natural killer cells to eliminate infected or cancerous cells.

The Perforin-Granzyme Pathway Involves