What happens to most of the secreted T₄?
A) It is phagocytized by target tissues.
B) It is converted into T3 after being peripherally stripped of one of its I atoms.
C) It is the major biologically active form of thyroid hormone at the cellular level.
D) It is split to form two DIT molecules, which are excreted in the urine.

Question

Quizplus · Accepted Answer

Most of the secreted T₄ is converted into T3 after being peripherally stripped of one of its I atoms. T3 is the major biologically active form of thyroid hormone at the cellular level, and it is responsible for most of the metabolic effects attributed to thyroid hormone.

What Happens to Most of the Secreted T₄