Given the following data for substance X (GFR = 125 mL/min,Tm = 125 mg/min,at a plasma concentration of 200 mg/100 mL),how much of substance X is filtered,reabsorbed,and excreted?
A) 125 mg/min filtered, 125 mg/min reabsorbed, 0 mg/min excreted
B) 200 mg/min filtered, 125 mg/min reabsorbed, 75 mg/min excreted
C) 250 mg/min filtered, 125 mg/min reabsorbed, 125 mg/min excreted
D) 250 mg/min filtered, 200 mg/min reabsorbed, 50 mg/min excreted

Question

Quizplus · Accepted Answer

The filtered load is calculated as GFR (125 mL/min) multiplied by plasma concentration (200 mg/100 mL = 2 mg/mL), which equals 250 mg/min. The maximum reabsorption (Tm) is 125 mg/min, so 125 mg/min is reabsorbed, and the remaining 125 mg/min is excreted.

Given the Following Data for Substance X (GFR = 125