Which of the following statements best supports the one gene-one enzyme hypothesis?
A) A mutation in a single gene can result in a defective protein.
B) Alkaptonuria results when individuals lack multiple enzymes involved in the catalysis of homogentisic acid.
C) Sickle-cell anemia results in normal hemoglobin.
D) Multiple antibody genes can code for different related proteins, depending on the splicing that takes place post-transcriptionally.

Question

Quizplus · Accepted Answer

The one gene-one enzyme hypothesis suggests that each gene is responsible for the production of a single enzyme. A mutation in a single gene leading to a defective protein supports this hypothesis by illustrating how the alteration of one gene can impact the function of one enzyme or protein, directly aligning with the hypothesis's core assertion.

Which of the Following Statements Best Supports the One Gene-One