Which of the following characterizes BRCA1 and BRCA2 as tumor-suppressor genes?
A) Their normal products participate in repair of DNA damage.
B) The mutant forms of either one of these prevent breast cancer.
C) The normal genes code for estrogen receptors.
D) They block penetration of breast cells by chemical carcinogens.

Question

Quizplus · Accepted Answer

BRCA1 and BRCA2 are involved in the repair of DNA damage, which is a crucial function in preventing the development of cancer. When DNA repair mechanisms are compromised due to mutations in these genes, cells are more likely to accumulate additional mutations that can lead to cancer.

Which of the Following Characterizes BRCA1 and BRCA2 as Tumor-Suppressor