Which of the following explains why introducing the MyoD protein into a fat cell causes that cell to become a muscle cell but adding it to a neuron will have no effect?
A) Fat cells are undifferentiated, the MyoD protein causes them to differentiate.
B) Neurons are a differentiation step after muscle cells, they cannot go "backwards."
C) Muscle-specific gene expression requires a protein that neurons do not make.
D) MyoD is causes positive feedback of MyoD expression in fats cells but not neurons.

Question

Quizplus · Accepted Answer

Muscle-specific gene expression, which is initiated by MyoD, requires additional proteins that are present in fat cells but not in neurons. This is why MyoD can convert fat cells into muscle cells but has no effect on neurons, as the latter lack the necessary cofactors for muscle gene activation.

Which of the Following Explains Why Introducing the MyoD Protein