Which of the following statements best explain why retroviral vectors for gene therapy may increase the patient's risk of developing cancer?
A) Retroviral vectors introduce proteins from the virus that alters control of the host cell's cell cycle.
B) Retroviral vectors do not express the genes that were introduced into a patient's cells.
C) Activating transcription of the retroviral vector's genes may result in spread of the virus throughout the body.
D) Integration of the retroviral vector's DNA into the genome may misregulate the expression of genes near the integration site.

Question

Quizplus · Accepted Answer

Retroviral vectors integrate their DNA into the host genome, which can disrupt or alter the expression of nearby genes. If these genes are involved in cell cycle control or tumor suppression, their misregulation can increase the risk of cancer.

Which of the Following Statements Best Explain Why Retroviral Vectors