Which of the following processes is part of the whole-genome shotgun approach to sequencing?
A) fragmenting genomic DNA at random sites
B) mapping the chromosomal location of cloned DNA fragments
C) using DNA primers with randomly generated sequences to begin sequencing reactions throughout the genome
D) focusing the efforts to sequence the genomes of new species by using DNA primers known to be conserved between other species

Question

Quizplus · Accepted Answer

The whole-genome shotgun approach involves randomly fragmenting the entire genome into smaller pieces, sequencing these fragments, and then assembling the sequences using computational methods.

Which of the Following Processes Is Part of the Whole-Genome