If a viral host cell has a mutation that interferes with the addition of carbohydrates to proteins during processing in the Golgi apparatus, which of the following processes is most likely to occur?
A) The viral envelope proteins would not have glycoproteins added to them and might not arrive at the host plasma membrane.
B) The viral capsid proteins would not have glycoproteins added to them and might not arrive at the host plasma membrane.
C) The viral core proteins would not have glycoproteins added to them and might not arrive at the host plasma membrane.
D) The virus would be unable to reproduce within the host cell.

Question

Quizplus · Accepted Answer

Glycosylation, the addition of carbohydrates to proteins, often occurs in the Golgi apparatus. Viral envelope proteins, which are glycoproteins, require this modification for proper function and localization, including incorporation into the host plasma membrane. Without glycosylation, these proteins may not be correctly processed or localized, impacting the virus's ability to assemble and exit the cell. Capsid and core proteins are not typically glycosylated, and the mutation described would not directly prevent viral reproduction within the host cell, only potentially affect the virus's ability to infect other cells.

If a Viral Host Cell Has a Mutation That Interferes