Which of the following statements best describes the effect of a mutation that knocks out the GTPase activity of a G protein?
A) The concentration of available GTP would decrease.
B) The number of G proteins in the cell would increase.
C) The G protein would be inactivated by a G protein-coupled receptor/signal molecule complex.
D) The G protein would always be active.

Question

Quizplus · Accepted Answer

GTPase activity is responsible for turning off G proteins by hydrolyzing GTP to GDP. If this activity is knocked out, the G protein cannot turn itself off and remains in its active GTP-bound state.

Which of the Following Statements Best Describes the Effect of a Mutation