Which of the following activities would be inhibited by a drug that specifically blocks the addition of phosphate groups to proteins?
A) binding of G proteins to G protein-coupled receptors
B) ligand-gated ion channel signaling pathways
C) adenylyl cyclase activity
D) receptor tyrosine kinase activity

Question

Quizplus · Accepted Answer

Receptor tyrosine kinases (RTKs) are enzymes that phosphorylate tyrosine residues on proteins, including themselves, as part of their activation process. A drug that blocks the addition of phosphate groups would directly inhibit the activity of RTKs by preventing their phosphorylation and subsequent activation.

Which of the Following Activities Would Be Inhibited by a Drug