A mutation that causes an increase in function in a tumor suppressor gene would not likely cause cancer because a tumor suppressor protein
A) normally promotes the cell cycle.
B) normally responds to growth factors.
C) activates a signal transduction pathway.
D) inactivates growth factors.
E) does not promote cell division.

Question

Quizplus · Accepted Answer

Tumor suppressor proteins function to inhibit cell division and promote cell cycle arrest, thereby preventing uncontrolled cell growth that can lead to cancer. An increase in the function of a tumor suppressor gene would enhance its ability to suppress cell division, not promote cancer.

A Mutation That Causes an Increase in Function in a Tumor