
What is NOT a reason that the kidneys are particularly prone to damage caused by immune complexes?
A) Kidney blood vessel wall cells have receptors for antibodies on them, which makes them take up antibodies or immune complexes from the bloodstream. This blocks the kidneys up and causes them to malfunction and become damaged.
B) Blood is pushed through the kidneys at a very high pressure. Any blockage of the vessels, such as what might be caused by immune complex deposits, can lead to ruptures/inflammation and damage of these organs.
C) While blood vessel walls do NOT have receptors for antibodies, large immune complexes forced through small diameter vessels can become embedded within them. This can trigger complement system inflammation and cell destruction.
D) Trapped immune complexes that initiate inflammation can attract neutrophils. The neutrophils degranulate in the area of the immune complexes, leading to cell/tissue destruction.
E) These are all reasons that the kidneys are very susceptible to damage caused by immune complexes.
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