What would be an appropriate response if an antigen is presented on MHC class II molecules?
A) An effector CD4 cell activates the presenting cell.
B) An effector CD8 cell activates the presenting cell.
C) An effector CD4 cell kills the presenting cell.
D) An effector CD8 cell kills the presenting cell.
E) An effector CD8 cell activates a naive CD4 cell.

Question

Quizplus · Accepted Answer

MHC class II molecules present antigens to CD4+ T cells, which then activate the presenting cell (e.g. a macrophage or B cell) to mount an immune response. This activation involves the secretion of cytokines and the upregulation of co-stimulatory molecules on the presenting cell. Choice B, C, D and E are incorrect as they refer to the response of CD8+ T cells, which are activated by antigens presented on MHC class I molecules.

What Would Be an Appropriate Response If an Antigen Is