Which of the following is the correct sequence of events in the interferon response?
1) IFN induces synthesis of inactive antiviral proteins (iAVPs).
2) Virus enters host cell (cell 1) and replicates, producing long dsRNA.
3) Activated AVPs induce apoptosis of infected cell.
4) dsRNA induces synthesis and secretion of IFN to neighboring cells.
5) Entry of virus into cell armed with iAVPs (cell 2) activates these proteins.
A) 2, 4, 1, 5, 3
B) 1, 2, 3, 4, 5
C) 3, 1, 2, 5, 4
D) 5, 4, 1, 2, 3
E) 2, 1, 4, 3, 5

Question

Which of the following is the correct sequence of events in the interferon response?
1) IFN induces synthesis of inactive antiviral proteins (iAVPs).
2) Virus enters host cell (cell 1) and replicates, producing long dsRNA.
3) Activated AVPs induce apoptosis of infected cell.
4) dsRNA induces synthesis and secretion of IFN to neighboring cells. 
5) Entry of virus into cell armed with iAVPs (cell 2) activates these proteins.
A) 2, 4, 1, 5, 3
B) 1, 2, 3, 4, 5
C) 3, 1, 2, 5, 4
D) 5, 4, 1, 2, 3
E) 2, 1, 4, 3, 5

Quizplus · Accepted Answer

The correct sequence of events in the interferon response is as follows: 
1) Virus enters host cell (cell 1) and replicates, producing long dsRNA.
2) dsRNA induces synthesis and secretion of IFN to neighboring cells.
3) IFN induces synthesis of inactive antiviral proteins (iAVPs).
4) Entry of virus into cell armed with iAVPs (cell 2) activates these proteins.
5) Activated AVPs induce apoptosis of infected cell. 
Therefore, the correct sequence is 2-4-1-5-3, which corresponds to choice A.

Which of the Following Is the Correct Sequence of Events