T cells undergo immune selection FOR potential antigen-reactive cells and selection AGAINST those cells that react strongly with self-antigens.

Question

Quizplus · Accepted Answer

T cell development includes positive and negative selection processes that ensure the production of T cells capable of recognizing and responding to foreign antigens while avoiding self-reactivity. T cells that react strongly with self-antigens are eliminated during negative selection, while those that demonstrate weak or no reactivity to self-antigens are allowed to progress and participate in the adaptive immune response.

T Cells Undergo Immune Selection FOR Potential Antigen-Reactive Cells and Selection