Which of the following contribute to the limitless diversity generated from a relatively fixed number of immunoglobulin genes?
A) hypermutation only
B) random heavy and light chain reassortment only
C) somatic recombination only
D) hypermutation, random heavy and light chain reassortment, and somatic recombination

Question

Quizplus · Accepted Answer

Immunoglobulin diversity is generated by the combination of several mechanisms: hypermutation introduces random point mutations in the variable region of the genes; somatic recombination creates new combinations of gene segments; and random heavy and light chain reassortment allows for the generation of diverse antibody molecules. Together, these mechanisms allow for the generation of a limitless diversity of antibodies from a relatively small number of immunoglobulin genes.

Which of the Following Contribute to the Limitless Diversity Generated