The drug cytochalasin B blocks the function of actin. Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?
A) spindle formation
B) spindle attachment to kinetochores
C) movement of chromosomes to the poles during anaphase
D) cleavage furrow formation and cytokinesis

Question

Quizplus · Accepted Answer

Cytochalasin B affects actin, which is involved in forming the contractile ring that causes cleavage furrow formation during cytokinesis. Therefore, the drug would disrupt the formation of the cleavage furrow and inhibit cytokinesis. It would not directly affect spindle formation or attachment to kinetochores or the movement of chromosomes to the poles.

The Drug Cytochalasin B Blocks the Function of Actin