How does the protein p53 prevent abnormal cell division if DNA repair fails?
A) It triggers the apoptosis of damaged cells.
B) It triggers the differentiation of injured cells.
C) It helps increase the concentration of DNA repair proteins.
D) It helps increase the transcription of DNA repair genes.

Question

Quizplus · Accepted Answer

p53 serves as a tumor suppressor by promoting cell cycle arrest, apoptosis, or senescence in response to DNA damage, thereby preventing the proliferation of cells with a mutated or damaged genome. In cases where DNA repair fails, p53 triggers the apoptosis of the damaged cells instead of allowing them to continue dividing with an altered genome. Therefore, option A is the correct answer.

How Does the Protein P53 Prevent Abnormal Cell Division If