How do glucocorticoids regulate the synthesis of cytokines?
A) by directly interacting with the genes for cytokines
B) by interacting with the transcription factors for cytokines
C) by both of these mechanisms
D) by neither of these mechanisms

Question

Quizplus · Accepted Answer

Glucocorticoids regulate the synthesis of cytokines both by directly interacting with the genes for cytokines and by interacting with the transcription factors for cytokines. They can bind to glucocorticoid response elements in the DNA to directly influence gene expression, and they can also modulate the activity of transcription factors that are involved in cytokine production, thereby indirectly affecting cytokine synthesis.

How Do Glucocorticoids Regulate the Synthesis of Cytokines